The concentration and purity of an optically active substance can be measured by a polarimeter. In fact, the polarization plane of a linearly polarized light ray will be modified by an optically active substance.
The degree of modification is determined by the molecular composition and is proportional to the concentration of quiral molecules present in the substance. The ability to modify the polarization plane of a linearly polarized light ray by an optically active substance is described by Biot's law.
Polarimetry is a highly sensitive and non-destructive method for determining the optical activity of inorganic and organic substances. It is an ideal method for measurements of expensive or unique samples. Polarimetry is widely used for laboratory monitoring in the chemical, petrochemical and food industries.
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